BGR-34 (Blood Glucose Regulator-34) is a scientifically validated polyherbal Ayurvedic formulation developed by the Council of Scientific & Industrial Research (CSIR), Government of India. This comprehensive formula is enriched with natural botanical extracts from 6 medicinal plants, providing 34 active phytocompounds that work synergistically to support effective carbohydrate metabolism.
BGR-34 represents a significant advancement in Ayurvedic diabetes management, combining traditional wisdom with modern scientific validation. It functions as a natural DPP-4 (dipeptidyl peptidase-4) inhibitor with cardio-protective action, effectively helping to maintain normal blood glucose levels while reducing the risk of long-term complications.1
Each coated tablet of BGR-34 weighs 620 mg and contains the following botanical extracts:2
| Ingredient | Botanical Name | Part Used | Quantity per Tablet | Primary Action |
|---|---|---|---|---|
| Daruharidra | Berberis aristata DC. | Stem | 75 mg | Acts as natural DPP-4 inhibitor; contains berberine |
| Vijaysar | Pterocarpus marsupium Roxb. | Heartwood | 25 mg | Improves carbohydrate metabolism; rich in flavonoids |
| Gudmar | Gymnema sylvestre R.Br. | Leaf | 25 mg | Suppresses hunger; supports glucose regulation |
| Manjeeth | Rubia cordifolia L. | Root | 25 mg | Restores antioxidant enzymes; cellular protection |
| Methika | Trigonella foenum-graecum L. | Seed | Not specified | Manages carbohydrate absorption and uptake |
| Giloy | Tinospora cordifolia (Willd.) Miers | Stem | Not specified | Boosts immune system; improves body resistance |
BGR-34 employs multiple mechanisms to support carbohydrate metabolism:1
DPP-4 Inhibition: The formulation contains berberine from Berberis aristata, which acts as a natural dipeptidyl peptidase-4 (DPP-4) inhibitor. This increases endogenous GLP-1 and GIP concentrations, enhancing insulin secretion.
Enzymatic Modulation: BGR-34 actively restores the function of various enzymes in the body, encouraging incretin actions and supporting proper carbohydrate metabolism.
Antioxidant Protection: The formulation provides potent antioxidant activity, protecting body cells and tissues from free radical damage and oxidative stress.
Organ Nourishment: BGR-34 nourishes and strengthens vital organs by supplementing various phytonutrients, supporting overall systemic health.
A rigorous clinical trial published in the Journal of Traditional and Complementary Medicine (2018) evaluated BGR-34's efficacy in 56 patients with type 2 diabetes over 16 weeks. The study was registered with the Clinical Trial Registry of India (CTRI/2016/11/007476).1
Key Findings:
| Parameter | BGR-34 Group | Placebo Group | Statistical Significance |
|---|---|---|---|
| Fasting Blood Glucose Reduction | 34.3% (196.0 to 129.3 mg/dL) | 13.2% (187.2 to 162.9 mg/dL) | p < 0.001 |
| Post-Prandial Blood Glucose Reduction | 35.5% (276.8 to 191.9 mg/dL) | 10.9% (294.9 to 262.6 mg/dL) | p < 0.001 |
| HbA1c Reduction | 20.31% (9.56 to 7.58) | 10.87% (9.91 to 8.86) | p = 0.001 |
Pre-clinical toxicity studies conducted on rats showed:1
The formulation was found to be clinically safe when used in therapeutic dosages under medical supervision.
Standard Dose: 2 tablets twice daily
Timing: 30 minutes before meals (before breakfast and before dinner)
Administration: Take with lukewarm water or as directed by your physician
Duration: For optimal results, consistent daily use for at least 3 months is recommended3
AIMIL Pharmaceuticals (India) Ltd.
Beato Health Science Private Limited
BGR-34 (Blood Glucose Regulator-34) is a polyherbal Ayurvedic formulation developed by the Council of Scientific & Industrial Research (CSIR), Government of India. It contains extracts from 6 medicinal plants yielding 34 active phytocompounds. The formulation was developed through rigorous scientific research and clinical trials conducted by CSIR-NBRI-CIMAP, representing a unique collaboration between traditional Ayurvedic knowledge and modern scientific validation.1
BGR-34 works as a natural DPP-4 (dipeptidyl peptidase-4) inhibitor, which helps increase endogenous GLP-1 and GIP concentrations, thereby enhancing insulin secretion. The formulation contains berberine from Berberis aristata, which is the key compound responsible for this DPP-4 inhibitory action. Additionally, BGR-34 provides cardio-protective action, helps maintain normal blood glucose levels, and offers antioxidant benefits to protect body cells and tissues from free radical damage.1
Each 620mg tablet contains extracts from 6 medicinal plants: Daruharidra (Berberis aristata) 75mg, Vijaysar (Pterocarpus marsupium) 25mg, Gudmar (Gymnema sylvestre) 25mg, Manjeeth (Rubia cordifolia) 25mg, Methika (Trigonella foenum-graecum), and Giloy (Tinospora cordifolia). These ingredients work synergistically to support carbohydrate metabolism through multiple mechanisms.2
The recommended dosage is 2 tablets twice a day, taken 30 minutes before meals (before breakfast and dinner), or as directed by a physician. For adults, this is the standard dose, while children may require adjusted dosing as per physician guidance. Consistent daily use for at least 3 months is recommended for optimal results.3
A clinical study published in the Journal of Traditional and Complementary Medicine (2018) showed that BGR-34 produced significant reductions: 34.3% reduction in fasting blood sugar (from 196.0 to 129.3 mg/dL), 35.5% reduction in post-prandial blood sugar (from 276.8 to 191.9 mg/dL), and 20.31% reduction in glycosylated hemoglobin HbA1c (from 9.56 to 7.58) compared to placebo over 16 weeks. All results were statistically significant (p < 0.001).1
BGR-34 is generally considered safe when taken as directed. Pre-clinical toxicity studies showed no adverse effects on liver, heart, or kidney function at therapeutic doses. Clinical studies reported no significant adverse hematological or biochemical abnormalities. However, individual responses may vary, and the formulation should be used under medical supervision, especially if you are taking other medications.1
Yes, BGR-34 can be used as an adjunct therapy with other oral hypoglycemic agents (OHGAs) such as metformin, sulfonylurea, or glitazones. The synergistic approach may help reduce dosage dependence on synthetic medications, thereby reducing the risk from their long-term usage. However, it is not recommended for patients on insulin therapy, and you should always consult your physician before combining medications.1
Store BGR-34 in a cool, dry place away from direct sunlight at a temperature around 25°C. Keep the bottle tightly closed and out of reach of children. Do not use if the seal is broken. Always check the expiry date on the package before use.4
While individual responses may vary, clinical studies showed significant improvements in blood glucose parameters within 16 weeks of consistent use. Some users report improvements in symptoms like fatigue and weakness within the first month. For optimal results, consistent daily use for at least 3 months is recommended, along with prescribed diet and lifestyle modifications.1
BGR-34 is not recommended for patients on insulin therapy, individuals with acute infections or chronic debilitating diseases, pregnant and lactating women, patients with severe hypertension, those with history of severe cardiovascular events or renal failure, and children under 25 years of age. Always consult a physician before starting any new supplement.1
Every effort is made to maintain the accuracy of all information. However, actual product packaging and materials may contain more and/or different information. It is recommended not to solely rely on the information presented. The information given on this website is based on Ayurvedic texts and modern research about the product. Viewers must seek physician's advice before taking the product and not go for self-medication.
Gupta BP, Sharma I, Kohli N, et al. Preliminary clinical assessment and non-toxicity evaluation of an ayurvedic formulation BGR-34 in NIDDM. J Tradit Complement Med. 2018;8(4):506-514. https://pmc.ncbi.nlm.nih.gov/articles/PMC6174273/ ↩↩↩↩↩↩↩↩↩↩↩
AIMIL Pharmaceuticals. BGR-34 Tablets Product Information. https://www.aimilpharma.life/products/bgr-34-tablets ↩↩
1mg. Aimil BGR-34 Tablet Carbohydrate Metaboliser R&D by CSIR Product Details. https://www.1mg.com/otc/aimil-bgr-34-tablet-carbohydrate-metaboliser-r-d-by-csir-100-each-otc322631 ↩↩
trueMeds. BGR-34 Tablet Storage and Usage Information. https://www.truemeds.in/otc/bgr-34-tablet-100-tm-tacr1-046210 ↩↩